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Like semaglutide, tirzepatide targets the glucagon-like peptide-1 (GLP-1) receptor to help regulate appetite and reduce calorie intake

Research has documented cases where patients pay higher out-of-pocket costs for lower-WAC biosimilars under certain co-insurance designs because the biosimilars lower list price means the co-insurance dollar amount is lower, but the originators rebate-driven net price may result in the originator having lower formulary tier placement